Skip to main content
. 2019 Mar 13;4(1):42–50. doi: 10.1089/can.2018.0051

FIG. 4.

FIG. 4.

(A) Pregnenolone (green), (B) estradiol (blue), and (C) hydrocortisone (orange) best BMs for rFAAH crystal structure 2VYA.pdb in the pocket situated in the hydrophobic region by the two helices α-18 and α-19. Highlighted are the residues involved in the binding. F432, crucial for substrate access, is not directly involved in the binding.