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. 2019 Mar 13;4(1):42–50. doi: 10.1089/can.2018.0051

Table 1.

Half Saturation Binding Lipid Concentration for Recombinant Rat Fatty Acid Amide Hydrolase/POPC Interaction in the Presence of Steroids

  30,000/1 POPC–steroid ratio 300/1 POPC–steroid ratio
L1/2 (μM) L1/2 vs. control (%) L1/2 (μM) L1/2 vs. control (%)
Control 60±6 100.00 60±6 100.00
Pregnenolone 21±2 35.00*** 35±5 58.33***
Progesterone 52±4 86.67 53±7 88.33
Hydrocortisone 34±3 56.67*** 49±3 81.67*
Testosterone 59±6 98.33 46±4 76.67*
Cortisone 61±6 101.67 46±4 76.67*
Estradiol 40±5 66.67* 61±7 101.67
***

Denotes p value < 0.001; *0.01< p value < 0.05.

POPC, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine.