Table 3.
Outcomes of Alternate Time Horizon, Adverse Event Rate, and Cannabis Wastage Analyses
| Usual care | First-line adjunctive cannabis | Second-line adjunctive cannabis | Third-line adjunctive cannabis | |
|---|---|---|---|---|
| Five-year time horizon | ||||
| Average QALYs | 2.024 | 2.057 | 2.098 | 2.088 |
| Average cost | $27,505 | $29,035 | $29,327 | $28,865 |
| ICER | REF | Dominated | $45,968 | $21,143 |
| Ten-year time horizon | ||||
| Average QALYs | 3.469 | 3.507 | 3.563 | 3.557 |
| Average cost | $47,937 | $49,926 | $50,333 | $49,853 |
| ICER | REF | Dominated | $81,591 | $21,834 |
| Alternate cannabis AE rates | ||||
| Average QALYs | 0.476 | 0.482 | 0.486 | 0.479 |
| Average cost | $6,379 | $7,643 | $7,167 | $6,688 |
| ICER | REF | Dominated | $73,193 | Ext. dominated |
| Cannabis wastage | ||||
| Average QALYs | 0.476 | 0.488 | 0.489 | 0.480 |
| Average cost | $6,383 | $7,875 | $7,430 | $6,797 |
| ICER | REF | Dominated | $83,865 | Ext. dominated |
All costs are in 2017 U.S. dollars. ICERs are calculated referent to the next least costly nondominated treatment option.