Table 4.
Levels and comparisons of ACE, ACE2, ACE/ACE2, Ang II and Ang-(1–7) in the HD patients with CVD and without CVD.
| HD with CVD (n = 119) |
HD without CVD (n = 241) |
|
|---|---|---|
| ACE (RFU/μL/h) | 145 ± 38 | 127 ± 40*** |
| ACE2 (RFU/μL/h) | 7.0 ± 1.5 | 9.9 ± 2.5*** |
| ACE/ACE2 | 21.5 ± 6.3 | 13.2 ± 4.0*** |
| Ang II (ng/mL) | 121 ± 33 | 98 ± 27*** |
| Ang–(1–7) (ng/mL) | 13.8 ± 4.3 | 15.6 ± 4.7*** |
Data were expressed as mean ± SD.
indicates p < .001 compared with the HD with CVD group.
ACE: angiotensin converting enzyme; ACE2: angiotensin converting enzyme; Ang II: angiotensin II; Ang-(1–7): angiotensin 1–7; CVD: cardiovascular diseases; HD: hemodialysis.