Fig. 6.

Schematic of the reinstatement dynamics predicted to bring about parallel inhibition of episodic memories and implicit influences (e.g., sensory, semantic, emotional) during memory intrusions. Cue input flows into the hippocampus (lower left), driving pattern completion (blue circle). Inhibitory control processes mediated by the right MFG target the hippocampus to suppress retrieval; if inhibition is too slow, pattern completion succeeds, sending re-entrant signals out of the hippocampus (large grey arrow) to reactivate traces in sensory, semantic, and emotion regions (colored circles). The particular cortical and sub-cortical regions reactivated depend on the specific event and the content represented. Intrusion-related reactivation is predicted to trigger parallel inhibition of these structures and the hippocampus by the right MFG (downward arrows), via polysynaptic pathways yet to be fully understood. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)