Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Mar 27;10:277. doi: 10.3389/fneur.2019.00277

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Metcalf, Huntsman, Garcia, Kochanski, Chikinda, Watanabe, Underwood, Vanegas, Smith, White and Bulaj.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Effects of music-based intervention on paw thickness (edema) following carrageenan administration in CD-1 mice. (A)—Carrageenan-injected (ipsilateral paws) show increased thickness (caliper measurement across the dorso-ventral aspect of the paw) compared to non-injected (contralateral) paws (MUSIC–blue; CONTROL–white). (B)—effects of music (MUSIC–blue; CONTROL–white) on activity of Cannabidiol (CBD, 100 mg/kg) following i.p. administration. CBD was administered 120 min prior to testing. Edema was observed following carrageenan in animals exposed to control conditions whereas music-exposed and CBD-treated animals show a diminished edema. N = 6–8 per group. ^***P < 0.001. Data were analyzed using a two-way ANOVA followed by a Bonferroni post-hoc test.