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. 2019 Mar 27;10:277. doi: 10.3389/fneur.2019.00277

Table 1.

Examples of music-based interventions studied in rodents.

Species Main outcomes References
Mouse Modification of expression of multiple genes and improved memory (52)
Mouse Decreased anxiety in some genotypes and increased TrkB in all genotypes (44)
Mouse Antidepressant activity in combination with enriched environment housing (53)
Rats Higher pain thresholds and smaller tumors in bone cancer model (43)
Rat Significantly improved spatial memory impairment caused by status epilepticus (54)
Rat Decreased seizure frequency and number of high-frequency EEG spikes (34)
Rat Lowered heart rate in hypertensive animals (55)
Rat Modulation of BDNF expression in the hippocampus and hypothalamus (56, 57)
Rat Reduced metastatic nodules in animals injected with carcinosarcoma cells (58)