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. 2019 Mar 27;10:277. doi: 10.3389/fneur.2019.00277

Table 2.

Latency and edema differences (vs. contralateral) for both the control (ambient noise) and music-exposed CD-1 mice treated with various analgesic compounds and evaluated in the carrageenan model of inflammatory pain.

Compound Latency difference (sec) % of Contralateral paw thickness
Control Music Control Music
Vehicle 3.68 ± 0.68 2.79 ± 0.69 149.9 ± 5.6 137.6 ± 7.5
Galanin analog NAX 5055, 4 mg/kg 2.91 ± 0.61 1.65 ± 0.60 130.7 ± 2.5 119.5 ± 3.6*
Levetiracetam, 400 mg/kg 2.30 ± 0.58 2.07 ± 0.50 158.7 ± 5.8 137.9 ± 10.50
Cannabidiol, 100 mg/kg 2.18 ± 0.50 1.39 ± 0.64 167.0 ± 9.34 133.2 ± 1.83**
Ibuprofen, 25 mg/kg 2.57 ± 0.90 0.18 ± 0.48* 143.0 ± 4.60 135.9 ± 1.6

Means ± standard error, N = 5–8 per group.

*

P < 0.05 compared to control.

**

P < 0.01 compared to control. Data were analyzed by t-test (music-exposed vs. control for each treatment arm).