. Author manuscript; available in PMC: 2019 Apr 3.

Published in final edited form as: Appl In Vitro Toxicol. 2018 Mar 1;4(1):13–23. doi: 10.1089/aivt.2017.0025

Table 4.

Concentration of diazinon (DZ) and hydroxypyrimidine (PYR) in media and slices exposed to 340 nmoles DZ/well. Media only data samples were not incubated with a slice. Media and Slice samples were taken from the same well. The enzyme inhibitor 2-hydroxyquinoline (HQU) was present in the media of the bottom group of data, and was absent in the media of the top group of data. Values represent mean of three replicate samples.

Time hours	Media only (nmoles/well) DZ	Media (nmoles/well)		Slice (nmoles/slice)
Time hours	Media only (nmoles/well) DZ	DZ	Phase I PYR	DZ	Phase I PYR
Exposure without HQU
0	339.2	339.2	0	0	0
3	343.2	195.3	7.9	42.6	0
6	336.3	191.3	13.0	36.0	0
24	334.7	176.2	22.6	38.8	0
Exposure with HQU
0	357.0	357.0	0	0.0	0
3	348.1	219.1	5.2	40.8	0
6	320.0	210.0	10.3	35.8	0
24	304.3	198.2	10.6	32.8	0