Table 1. Demographics of patients from whom sputum was obtained.
Demographics of CF sputum donors. In total, 11 sputum samples were collected from 7 female and 4 male patients, one of whom was African American. The remaining 10 were Caucasian. Mean patient age was 28.5 years, ranging from 18-46 years of age. Spirometry data were obtained for each patient at the time of sample collection. The mean FEV1 % predicted value was 48.8 ranging from normal (90% predicted) to severely impaired (24% predicted) lung function. Additionally mean FVC was 2.7 L, and mean FEF25-75 was 0.96. Values of pH, % solids, and mean complex viscosity (η*) were also obtained for each sputum sample. Mean pH was 7.1 within a narrow range (6.3-7.7), mean % solids was 5.6 and the mean η* was 2.5 Pa·s. Sputum was collected from patients with CF according to UNC IRB protocol #15-2431.
Category | Mean or Count (Std. Dev.) |
Range |
---|---|---|
# Patients (male) | 11 (4) | - |
Age (years) | 28.5 (9.6) | 18-46 |
FEV1 % Predicted | 48.8 (22.0) | 24-90 |
FVC (L) | 2.7 (1.0) | 1.7-4.3 |
FEF25-75 | 0.96 (0.82) | 0.3-2.7 |
pH | 7.1 (0.42) | 6.3-7.7 |
% solids | 5.6 (2.5) | 2.3-10.6 |
η* (Pa·s) | 2.5 (1.5) | 0.65-4.5 |