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. 2019 Apr 3;20:119. doi: 10.1186/s12882-019-1297-y

Table 3.

Multivariable logistic regression analysis presenting associations between log klotho and metabolic syndrome

Variable Model Aa Model Bb
Adjusted OR (95% CI) Adjusted OR (95% CI)
Log klotho 0.44 (0.25–0.80)d 0.44 (0.23–0.82)d
Age (per year) 1.03 (1.02–1.04)d 1.03 (1.02–1.04)d
Sex (male vs. female) 1.15 (0.94–1.41) 1.13 (0.91–1.40)
eGFR (per mL/min/1.73m2) 1.00 (0.99–1.00)
Overt proteinuriac 1.26 (1.01–1.58)d

OR Odds ratio, CI confidence interval, eGFR estimated glomerular filtration rate by CKD-EPI creatinine equation

aModel A adjusted for log klotho, age, and sex

bModel B adjusted for covariates in model A plus eGFR, and overt proteinuria

c24-hour urine protein > 500 mg/day

dsignificant association with MS (P < 0.05). P < 0.05 was considered significant