Table 2.
Correlation of ENS-653 expression of with clinicopathologic variables of PTC patients
| Characteristics | ENS-653 expressiona | P-value | |
|---|---|---|---|
| Low | High | ||
| (n = 22) | (n = 64) | ||
| Age (years) | 51.5 ± 13.2 | 57.2 ± 13.3 | 0.088* |
| Gender [n(%)] | 0.833† | ||
| Female | 16 (72.7) | 48 (75.0) | |
| Male | 6 (27.3) | 16 (25.0) | |
| Histological subtypes [n(%)] | 1.000§ | ||
| Classic | 21 (95.5) | 62 (96.9) | |
| Follicular | 1 (4.5) | 2 (3.1) | |
| Tumor size [n(%)] | < 0.001† | ||
| < 2 cm | 14 (63.6) | 15 (23.4) | |
| ≥2 cm | 8 (36.4) | 49 (76.6) | |
| Extrathyroidal extension [n(%)] | 2 (9.1) | 7 (10.9) | 1.000§ |
| Multifocality [n(%)] | 6 (27.3) | 17 (26.6) | 0.948† |
| Coexistent HTb [n(%)] | 5 (22.7) | 15 (23.4) | 0.946† |
| T Stage [n(%)] | 0.856§ | ||
| T1 | 14 (22.7) | 15 (17.2) | |
| T2 | 7 (72.7) | 46 (78.1) | |
| T3 | 1 (4.5) | 2 (3.1) | |
| T4 | 0 (0.0) | 1 (1.6) | |
| N1 [n(%)] | 9 (40.9) | 27 (42.2) | 0.916† |
| M1 [n(%)] | 0 (0.0) | 4 (6.2) | 0.568§ |
| Clinical Stage [n(%)] | 0.001§ | ||
| I | 11 (50.0) | 8 (12.5) | |
| II | 2(9.1) | 26(40.6) | |
| III | 8(36.4) | 25(39.1) | |
| IV | 1 (4.5) | 5 (7.8) | |
aFold change(FC) (tumor tissues relative to normal tissues) is greater than or equal to 2.0 for high expression, and less than 2.0 for low expression
bHashimoto’s thyroiditis
*P values were calculated by Student’s t test
†P values were calculated by χ2 test
§P values were calculated by Fisher exact test