Table 1.

Summary of craniovascular nerve fibers and their vasoactive neuropeptides involved in migraine and cluster headache.

Craniovascular nerve fiber localization	Vasoactive neuropeptide/ neurotransmitter
Trigeminal sensory nerve fibers	Calcitonin gene-related peptide (CGRP)
	Substance P (SP)
	Neurokinin A (NKA)
	Pituitary adenylate cyclase-activating peptide (PACAP)
	Nitric oxide synthase (NOS)
Parasympathetic nerve fibers	Vasoactive intestinal peptide (VIP)
	PACAP
	Neuropeptide Y (NPY)
	Acetylcholine
	NOS
Sympathetic nerve fibers	Noradrenaline
	NPY
	Adenosine triphosphate (ATP)