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. 2019 Apr 1;33(7-8):382–387. doi: 10.1101/gad.323105.118

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© 2019 Zhang et al.; Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genesdev.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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Figure 4. — Putative H3K27m3 associated PEGs and proposed model for mechanisms underlying paternal-biased expression. (A) A genome browser view showing H3K27me3 enrichment in morula and DNA methylation levels in oocyte, sperm, and morula at FAM101A locus. Red square represents the SNP identified from H3K27me3 CUT&RUN data. (B) Schematic model showing paternal allelic gene expression can be regulated by either allelic DNA methylation or allelic H3K27me3 in human morulae.