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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Metabolism. 2019 Jan 31;94:59–68. doi: 10.1016/j.metabol.2019.01.016

Table 2.

Core Body Temperature, Energy Expenditure, and Urinary Catecholamines Measurements by Dietary Intervention.

Fasting
FST (n=53)
Energy
Balance EBL (n=36)
High-fat OF
FNP (n=25)
High-carbohydrate OF
CNP (n=24)
avgCBT (°C) 36.81±0.14
(36.51, 37.10)
36.86±0.13
(36.56, 37.22)
36.93±0.10
(36.78, 37.14)a,b
37.01±0.12
(36.75, 37.23)a,b
ΔavgCBT (°C) N/A 0.06±0.11
(−0.11, 0.37)
0.13±0.14b
(−0.12, 0.39)
0.19±0.13b
(−0.05, 0.42)
Daytime CBT (°C)e 36.81±0.21
(36.44, 37.41)
36.88±0.21
(36.49, 37.36)
36.92±0.17
(36.63, 37.23)
37.02±0.12a
(36.75, 37.23)
Night CBT(°C)f 36.64±0.19
(36.23, 37.26)
36.55±0.16
(36.16, 36.84)
36.65±0.14
(36.26, 36.92)
36.71±0.17a
(36.38, 37.07)
24-h EE (kcal/day) 1895±219
(1469, 2390)
2059±274
(1573, 2732)
2148±227a
(1764, 2631)
2308±329a,b
(1728, 2884)
SLEEP (kcal/24h) 1607±192
(1231, 2373)
1629±210
(1211, 2303)
1739±166a
(1425, 2064)
1772±237a,b
(1411, 2273)
Energy Intake (kcal/24h) N/A 2125±287
(1622, 2800)
3982±465
(3148, 4920)
3961±538
(3022, 4905)
Energy Balance (kcal/day) −1895±219
(−2390, −1469)
65±145a
(−91, 651)
1835±166a,b,c
(1425, 2064)
1653±360a,b
(331, 2063)
DIT (kcal/day) N/A 160±93a
(−1.00, 405.00)
296±119a,b
(65.00, 575.00)
444±146a,b
(195.00, 870.00)
TEF (% of Energy Intake) N/A 7.3±3.8
(−0.06, 15.73)
7.40±2.72c
(1.54, 11.93)
11.3±3.6b
(6.2, 21.0)
RQ (ratio) 0.79±0.03
(0.74, 0.90)
0.87±0.03a
(0.83, 0.94)
0.85±0.03a,c
(0.80, 0.91)
0.94±0.03a,b
(0.88, 1.00)
24-h SPA (%) 6.1±3.5
(0.5, 18.3)
5.6±3.1
(0.6, 16.1)
6.1±2.7
(0.6, 12.8)
6.5±3.3
(0.9, 15.5)
Ambient temperature (°C) 24.06±1.17
(20.90, 26.20)
24.18±1.05
(22.00, 26.19)
23.94±1.15
(21.40, 26.31)
24.27±1.30
(22.00, 26.40)
Norepinephrine (μg/24h)d 21.0 (15.4, 28.0) 25.4 (20.8, 33.8)a 26.0 (15.6, 34.6) 21.4 (17.6, 32.4)
Normetanephrine (μg/24h)d 183.4 (142.9, 243.0) 227.2 (180.2, 340.6)a 267.0 (199.8, 337.6)a,c 188.2 (144.4, 270.7)
Epinephrine (μg/24h)d 5.9 (4.0, 9.2) 4.0 (2.6, 6.0)a 3.9 (3.0, 5.2)a 3.3 (3.1, 5.5)a
Metanephrine (μg/24h)d 121.2 (76.2, 177.8) 129.3 (86.9, 188.1) 130.8 (86.8, 177.6) 93.3 (81.6, 174.3)
Plasma insulin (mU/L) −3.3 (−4.2, −2.4)g 0.7 (−0.7, 2.0) 0.1 (−1.2, 1.3) 3.3 (1.3, 5.2)g

Data presented as mean±SD with minimum and maximum values in parenthesis, except for urinary catecholamines that are presented as median with interquartile range in parenthesis and insulin that is presented as mean with 95% CI in parenthesis.

a

p < 0.05 versus FST,

b

p < 0.05 versus EBL,

c

p < 0.05 versus CNP,

d

n=29 for FST, n=18 for EBL, n=14 for CNP, n=15 for FNP.

e

Daytime CBT calculated between 08:00 and 23:00.

f

Night-time CBT calculated from 23:30 through 05:00, the same time period used to calculate SLEEP.

g

p < 0.05 versus zero by Student’s t test for parametric data or Wilcoxon test for non-parametric data.

Abbreviations: OF, overfeeding; avgCBT, mean 24-h core body temperature; ΔavgCBT, change in CBT from fasting; 24h EE, 24-hour energy expenditure; SLEEP, sleeping EE; RQ, respiratory quotient; 24h SPA, 24-hours spontaneous physical activity; TEF, thermic effect of food; DIT, diet-induced thermogenesis