Table 2.
Participant characteristics and self-reported perceived fertility potential
| Participant Characteristics† | More/As fertile n (%) n=210 | Less fertile n (%) n=179 | Infertile n (%) n=94 | P-value |
|---|---|---|---|---|
| Current age (y) | ||||
| 18 – 24 | 8 (3.9) | 21 (11.9) | 3 (3.3) | |
| 25 – 30 | 44 (21.2) | 41 (23.3) | 23 (25.3) | 0.001 |
| 31 – 35 | 82 (39.4) | 68 (38.6) | 24 (26.4) | |
| 36 – 41 | 74 (35.6) | 46 (26.1) | 41 (45.1) | |
| Race | ||||
| White | 158 (75.2) | 132 (73.7) | 70 (74.7) | |
| Black | 6 (2.9) | 1 (0.6) | 3 (3.2) | 0.39 |
| Asian/Pacific Islander | 14 (6.7) | 13 (7.3) | 2 (2.1) | |
| Mixed/Other | 32 (15.2) | 33 (18.4) | 19 (20.2) | |
| Hispanic ethnicity | 47 (22.3) | 41 (22.9) | 21 (22.3) | 0.96 |
| BMI (kg/m2) | ||||
| < 18.5 | 42 (20.9) | 50 (28.3) | 25 (26.9) | |
| 18.5 – 24.9 | 98 (48.8) | 73 (41.2) | 41 (44.1) | 0.75 |
| 25 – 29.9 | 31 (15.4) | 26 (14.7) | 13 (14.0) | |
| ≥ 30 | 30 (14.9) | 28 (15.8) | 14 (15.1) | |
| Education: college graduate | 164 (78.1) | 135 (75.4) | 66 (70.2) | 0.20 |
| Income | ||||
| Less than $51,000 | 43 (20.5) | 48 (26.8) | 22 (23.4) | 0.48 |
| Greater than $51,000 | 156 (74.3) | 122 (68.2) | 63 (67.0) | |
| Current health insurance | 201 (95.7) | 169 (94.4) | 90 (95.7) | 0.84 |
| Cancer Characteristics | ||||
| Cancer category | ||||
| Breast | 40 (19.1) | 48 (26.8) | 25 (26.6) | |
| Leukemia/Lymphoma | 63 (30.0) | 59 (33.0) | 31 (33.0) | |
| Gynecologic†† | 10 (4.8) | 7 (3.9) | 11 (11.7) | 0.02 |
| Gastrointestinal††† | 5 (2.4) | 6 (3.4) | 3 (3.2) | |
| Bone/soft tissue | 14 (6.7) | 12 (6.7) | 7 (7.5) | |
| Thyroid, Skin | 78 (37.1) | 47 (26.3) | 17 (18.1) | |
| Chemotherapy | 109 (51.9) | 121 (67.6) | 74 (78.7) | <0.001 |
| Bone Marrow Transplant | 1 (0.5) | 4 (2.2) | 10 (10.6) | <0.001 |
| Surgical cancer therapy | 150 (71.4) | 124 (69.3) | 58 (61.7) | 0.16 |
| Radiation | 99 (47.1) | 87 (48.6) | 49 (52.1) | 0.65 |
| Age at cancer diagnosis | ||||
| Less than 18 | 25 (12.0) | 20 (11.4) | 8 (8.8) | |
| 18 – 24 | 74 (35.6) | 61 (34.7) | 28 (30.8) | 0.34 |
| 25 – 35 | 109 (52.4) | 95 (53.9) | 55 (60.4) | |
| Years since cancer diagnosis | ||||
| < 2 | 19 (9.1) | 30 (16.8) | 15 (16.0) | |
| 2 – 5 | 41 (19.5) | 55 (30.7) | 27 (28.7) | 0.002 |
| ≥ 5 | 150 (71.4) | 94 (52.5) | 52 (55.3) | |
| Reproductive Characteristics | ||||
| History of infertility | 11 (5.2) | 28 (15.6) | 23 (24.5) | <0.001 |
| Prior to cancer diagnosis | 6 (2.9) | 14 (7.8) | 13 (13.8) | <0.001 |
| After cancer diagnosis | 5 (2.4) | 19 (10.6) | 15 (15.9) | |
| Menses within the last year | ||||
| 0 – 3 | 38 (18.1) | 33 (18.4) | 37 (39.4) | |
| 4 – 9 | 32 (15.2) | 32 (17.9) | 18 (19.2) | <0.001 |
| 10 – 12 | 140 (66.7) | 114 (63.7) | 39 (41.5) | |
| Menses within the last year* | ||||
| 0 – 3 | 17 (13.7) | 14 (14.4) | 31 (40.3) | |
| 4 – 9 | 15 (12.1) | 14 (14.4) | 11 (14.3) | <0.001 |
| 10 – 12 | 92 (74.2) | 69 (71.2) | 35 (45.4) | |
| Ever pregnant | 142 (67.6) | 72 (40.2) | 43 (45.7) | <0.001 |
| Times pregnant | ||||
| 1 | 31 (21.8) | 29 (40.3) | 10 (23.2) | 0.03 |
| 2 | 65 (45.8) | 22 (30.5) | 15 (34.9) | |
| ≥ 3 | 46 (32.4) | 21 (29.2) | 18 (41.9) | |
| Ever live birth | 129 (61.4) | 57 (31.8) | 39 (41.5) | <0.001 |
| Recent intercourse** | 192 (91.4) | 153 (85.5) | 81 (83.2) | 0.15 |
†
Data missing for some variables
††
Gynecologic cancer = cervix, uterus, ovary
†††
Gastrointestinal cancer = pancreas, gallbladder, stomach, small intestine, colon, appendix, rectum
*
Excluding participants on birth control pills, depot medroxyprogesterone, implant, IUD, contraceptive patch and contraceptive ring
**
Recent intercourse indicates heterosexual intercourse within 3 months of completing the enrollment questionnaire