. Author manuscript; available in PMC: 2020 Apr 1.

Published in final edited form as: Genet Epidemiol. 2019 Feb 11;43(3):276–291. doi: 10.1002/gepi.22194

Table 5:

Simulation for gene expression data using correlations calculated from NSCLC data. (n, p) = (300, 505). 50 genes have nonzero regression coefficients. 5 clinical covariates are not subject to selection. mean(sd) of true positives (TP) and false positives (FP) based on 100 replicates.

		LAD_Network	LAD_MCP	LAD_LASSO	Network	MCP	LASSO
Error1	TP	43.10(6.57)	43.32(3.41)	41.01(6.91)	47.12(3.08)	39.67(3.12)	45.91(1.65)
	FP	1.40(2.00)	3.02(3.77)	5.68(9.65)	0.83(1.44)	1.44(2.27)	23.01(12.09)
Error2	TP	36.44(9.83)	33.73(6.75)	34.46(5.28)	25.23(6.41)	11.27(3.03)	19.72(5.92)
	FP	13.80(25.85)	34.36(55.80)	23.14(42.02)	43.94(34.98)	15.86(18.95)	14.23(8.96)
Error3	TP	41.51(8.41)	39.23(6.68)	38.17(6.52)	38.20(10.43)	24.93(9.19)	35.45(8.77)
	FP	4.75(6.41)	11.10(12.24)	13.47(20.48)	13.66(37.16)	8.64(34.40)	22.71(21.76)
Error4	TP	42.13(7.50)	38.58(6.86)	39.72(6.14)	34.56(10.60)	19.90(9.03)	30.23(9.58)
	FP	7.03(9.27)	13.33(25.09)	16.63(28.77)	30.02(72.28)	13.17(42.50)	19.57(27.40)