Table 6:
Simulation for SNP data (n, p) = (300, 505) under AR structures. 50 genes have nonzero regression coefficients. 5 clinical covariates are not subject to selection. The SNPs have AR structure with ρ = 0.5 (upper panel) and ρ = 0.8 (lower panel). mean(sd) of true positives (TP) and false positives (FP) based on 100 replicates.
| LAD_Network | LAD_MCP | LAD_LASSO | Network | MCP | LASSO | ||
|---|---|---|---|---|---|---|---|
| AR ρ = 0.5 | |||||||
| FP | 8.83(5.80) | 9.33(7.71) | 106.03(37.94) | 9.13(6.26) | 8.77(5.17) | 84.53(11.25) | |
| FP | 23.93(40.56) | 57.97(95.48) | 110.17(66.55) | 32.03(86.43) | 45.67(126.72) | 23.67(39.83) | |
| FP | 9.00(6.44) | 15.93(26.06) | 107.77(43.29) | 8.50(5.76) | 8.30(5.45) | 58.40(34.86) | |
| FP | 10.17(6.86) | 27.17(41.85) | 109.70(45.23) | 6.73(6.10) | 6.07(6.49) | 40.63(41.16) | |
| AR ρ = 0.8 | |||||||
| FP | 3.80(2.96) | 3.47(2.66) | 104.20(30.42) | 10.00(7.89) | 6.67(3.39) | 60.00(12.99) | |
| FP | 12.20(8.02) | 44.20(83.64) | 105.40(32.2) | 35.30(89.14) | 43.57(111.1) | 25.77(42.43) | |
| FP | 6.77(5.88) | 6.10(10.6) | 105.63(28.03) | 18.97(16.06) | 20.83(65.59) | 60.93(29.47) | |
| FP | 5.67(4.56) | 10.30(21.71) | 120.90(48.61) | 19.77(13.39) | 7.57(6.82) | 50.30(31.1) | |