Table 7:
Simulation for SNP data (n, p) = (300, 505) under banded structures. 50 genes have nonzero regression coefficients. 5 clinical covariates are not subject to selection. The SNPs have Banded.1 (upper panel) or Banded.2 structure (lower panel) with ρ = 0.5. mean(sd) of true positives (TP) and false positives (FP) based on 100 replicates.
LAD_Network | LAD_MCP | LAD_LASSO | Network | MCP | LASSO | ||
---|---|---|---|---|---|---|---|
Banded.1 | ρ = 0.5 | ||||||
FP | 9.10(5.92) | 13.53(21.54) | 91.63(43.74) | 8.27(5.30) | 8.53(6.22) | 81.93(12.6) | |
FP | 14.93(13.16) | 57.30(93.44) | 97.63(51.97) | 17.30(60.78) | 24.20(89.50) | 13.10(27.14) | |
FP | 8.00(4.61) | 18.57(38.32) | 101.23(52.47) | 8.13(7.21) | 6.63(6.19) | 53.10(37.71) | |
FP | 16.37(12.94) | 18.30(36.76) | 108.90(39.14) | 7.07(7.91) | 6.53(5.78) | 56.57(30.96) | |
Banded.2 | ρ = 0.5 | ||||||
FP | 10.83(7.68) | 9.17(7.45) | 113.63(46.59) | 9.63(6.7) | 9.30(4.23) | 84.00(12.91) | |
FP | 17.27(10.43) | 76.43(122.77) | 93.57(49.76) | 5.10(10.5) | 5.00(10.3) | 11.40(15.40) | |
FP | 10.60(7.02) | 15.63(38.21) | 117.63(38.53) | 9.80(7.23) | 9.50(7.10) | 66.77(37.00) | |
FP | 18.77(13.23) | 41.57(69.17) | 109.73(42.16) | 11.13(26.16) | 12.90(30.37) | 45.90(38.12) |