Fig. 2.

Effects of Rosi on lipolytic rates and FA oxidative capacity in human adipocytes. A: Glycerol accumulation in culture media during the final 24 h. *P < 0.05 with paired t-tests after two-way ANOVA, n = 6. B: Lipolytic capacity under basal and stimulated conditions was measured in isolated adipocytes from control or Rosi-treated Om tissues. Data are expressed as the mean ± SEM of seven experiments. *P < 0.05 (control vs. Rosi); ^#P < 0.05 compared with the basal within each condition (post hoc paired t-tests) after RM-ANOVA (F = 3.22, P = 0.004). C: FA oxidation rates (¹⁴C-oleate oxidation to ¹⁴CO₂) in adipose tissues cultured with or without Rosi. Data are expressed as the mean ± SEM of four experiments. *P < 0.05, **P < 0.01 with paired t-tests. D: Expression levels of mitochondrial ETC proteins were measured in isolated mitochondria after 7 days of treatment with Rosi and a representative Western blot of three (Om) or four subcutaneous (SC) are shown.