Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
atRA activates MAPK pathways to regulate CYP7A1 expression. A: HepaRG cells and human hepatocytes were treated with atRA (1 µM) for the time periods indicated. Protein levels were determined by Western blot analysis. B: mRNA levels of CYP7A1 in the cells were measured by qPCR. (n = 3, mean ± SD). *** P < 0.001 versus DMSO-treated group. PD, PD98059; SB, SB203580; SP, SP600125.
