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. 2019 Jan 4;285(4):436–445. doi: 10.1111/joim.12868

Table 3.

Haematuria cancer risk score cut‐offs with corresponding sensitivity, specificity, true positive and negative and false positive and negative derived from the ROC curve in the development and validation cohort

Cut‐off Development cohort Validation cohort
TP FN FP TN Specificity (95% CI) Sensitivity (95% CI) TP FN FP TN Specificity (95% CI) Sensitivity (95% CI)
3.240 282 3 3058 196 0.060 (0.053, 0.069) 0.993 (0.982, 1.000) 70 0 517 69 0.118 (0.092, 0.143) 1.000 (1.000, 1.000)
3.897 279 6 2748 506 0.156 (0.143, 0.168) 0.979 (0.961, 0.993) 69 1 428 158 0.270 (0.232, 0.306) 0.986 (0.957, 1.000)
4.015 277 8 2656 598 0.184 (0.170, 0.198) 0.972 (0.954, 0.989) 69 1 406 180 0.305 (0.268, 0.346) 0.986 (0.957, 1.000)
4.334 274 11 2380 874 0.269 (0.254, 0.284) 0.961 (0.937, 0.982) 67 3 336 250 0.425 (0.386, 0.468) 0.957 (0.914, 1.000)
4.386 271 14 2337 917 0.282 (0.267, 0.298) 0.951 (0.923, 0.975) 66 4 324 262 0.445 (0.406, 0.486) 0.943 (0.886, 0.986)
4.492 268 17 2239 1015 0.312 (0.296, 0.329) 0.940 (0.912, 0.965) 65 5 296 290 0.494 (0.454, 0.536) 0.929 (0.871, 0.986)
4.559 265 20 2171 1083 0.333 (0.317, 0.349) 0.930 (0.898, 0.958) 65 5 285 301 0.512 (0.473, 0.556) 0.929 (0.871, 0.986)
4.681 263 22 2050 1204 0.370 (0.354, 0.387) 0.923 (0.891, 0.951) 65 5 261 325 0.555 (0.514, 0.596) 0.929 (0.871, 0.986)
4.681 262 23 2050 1204 0.370 (0.354, 0.387) 0.919 (0.888, 0.951) 65 5 261 325 0.555 (0.514, 0.596) 0.929 (0.871, 0.986)
4.916 256 29 1806 1448 0.445 (0.428, 0.462) 0.898 (0.863, 0.930) 60 10 216 370 0.631 (0.592, 0.671) 0.857 (0.771, 0.929)

95% CI, 95% confidence interval; FN, false negative; FP, false positive; TN, true negative; TP, true positive.