Table 3.
Cut‐off | Development cohort | Validation cohort | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
TP | FN | FP | TN | Specificity (95% CI) | Sensitivity (95% CI) | TP | FN | FP | TN | Specificity (95% CI) | Sensitivity (95% CI) | |
3.240 | 282 | 3 | 3058 | 196 | 0.060 (0.053, 0.069) | 0.993 (0.982, 1.000) | 70 | 0 | 517 | 69 | 0.118 (0.092, 0.143) | 1.000 (1.000, 1.000) |
3.897 | 279 | 6 | 2748 | 506 | 0.156 (0.143, 0.168) | 0.979 (0.961, 0.993) | 69 | 1 | 428 | 158 | 0.270 (0.232, 0.306) | 0.986 (0.957, 1.000) |
4.015 | 277 | 8 | 2656 | 598 | 0.184 (0.170, 0.198) | 0.972 (0.954, 0.989) | 69 | 1 | 406 | 180 | 0.305 (0.268, 0.346) | 0.986 (0.957, 1.000) |
4.334 | 274 | 11 | 2380 | 874 | 0.269 (0.254, 0.284) | 0.961 (0.937, 0.982) | 67 | 3 | 336 | 250 | 0.425 (0.386, 0.468) | 0.957 (0.914, 1.000) |
4.386 | 271 | 14 | 2337 | 917 | 0.282 (0.267, 0.298) | 0.951 (0.923, 0.975) | 66 | 4 | 324 | 262 | 0.445 (0.406, 0.486) | 0.943 (0.886, 0.986) |
4.492 | 268 | 17 | 2239 | 1015 | 0.312 (0.296, 0.329) | 0.940 (0.912, 0.965) | 65 | 5 | 296 | 290 | 0.494 (0.454, 0.536) | 0.929 (0.871, 0.986) |
4.559 | 265 | 20 | 2171 | 1083 | 0.333 (0.317, 0.349) | 0.930 (0.898, 0.958) | 65 | 5 | 285 | 301 | 0.512 (0.473, 0.556) | 0.929 (0.871, 0.986) |
4.681 | 263 | 22 | 2050 | 1204 | 0.370 (0.354, 0.387) | 0.923 (0.891, 0.951) | 65 | 5 | 261 | 325 | 0.555 (0.514, 0.596) | 0.929 (0.871, 0.986) |
4.681 | 262 | 23 | 2050 | 1204 | 0.370 (0.354, 0.387) | 0.919 (0.888, 0.951) | 65 | 5 | 261 | 325 | 0.555 (0.514, 0.596) | 0.929 (0.871, 0.986) |
4.916 | 256 | 29 | 1806 | 1448 | 0.445 (0.428, 0.462) | 0.898 (0.863, 0.930) | 60 | 10 | 216 | 370 | 0.631 (0.592, 0.671) | 0.857 (0.771, 0.929) |
95% CI, 95% confidence interval; FN, false negative; FP, false positive; TN, true negative; TP, true positive.