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. 2018 Oct 4;180(3):586–596. doi: 10.1111/bjd.17088

Figure 2.

Figure 2

Levels of cytokines and chemokines in the stratum corneum of children with AD and healthy controls (CTRL). Stratum corneum: n = 66 (AD) and n = 13 (healthy); plasma: n = 47 (AD) and n = 20 (healthy). The values are log transformed, shown as boxplots with Tukey‐style whiskers. Differences in cytokine and chemokine levels between healthy children and children with AD were determined by two‐tailed Welch's t‐test or two‐tailed Mann–Whitney test (raw data in Table S2; see Supporting Information). Benjamini–Hochberg corrected P‐values: ****P < 0·0001, ***P < 0·001, **P < 0·01, *P < 0·05. GM‐CSF, granulocyte–macrophage colony‐stimulating factor; IL, interleukin; PIGF, placental growth factor; SAA, serum amyloid A; sICAM, soluble intercellular adhesion molecule; sVCAM, soluble vascular cell adhesion molecule; VEGF, vascular endothelial growth factor.