Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Feb 8;218(4):1369–1389. doi: 10.1083/jcb.201806065

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 Mason et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 5. — YAP and TAZ modulate actin polymerization and stress fiber formation. (A) F-actin, visualized with Alexa Fluor 488 phalloidin. (B) Fluorescent intensity line profiles of phalloidin, three cells per condition. (C) F- and G-actin visualized by Alexa Fluor 488 and 594 phalloidin and DNase I, respectively. (D) F- and G-actin intensity (P > 0.11) and F-/G-actin ratio per cell, normalized to siControl; n = 60 cells; P < 0.005; ANOVA with Tukey’s post hoc test. (E) WT or YAP/TAZ conditional knockout (cKO) BMSCs 14 d after osteoinduction actin visualized with Alexa Fluor 488 phalloidin. (F) Actin fluorescent intensity; line scans are the average of three cells per condition, distance normalized to the largest cell in the set. (G) Line profile fluorescence. n = 39–60 cells; P < 0.0001; two-tailed unpaired Student’s t test. n.s., not significant. Repeated significance indicator letters (e.g., a–a) signify P > 0.05, while groups with distinct indicators (a vs. b; *) signify P < 0.05.