Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Mar 15;216(4):831–846. doi: 10.1084/jem.20181604

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 Kimura et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 5. — Defect in M cell maturation in Sox8^−/− results from epithelium-intrinsic defect. (A and B) Organoids from small intestinal crypts of Sox8^+/+ and Sox8^−/− mice were cultured with or without RANKL for 3 d. (A) Immunostaining images for GP2 (green) on organoids. Bars, 100 µm. (B) qPCR analysis of M cell–associated genes expressed in the organoid cultures. Values are presented as the mean ± SD; **, P < 0.01; *, P < 0.05; n.s., not significant; unpaired two-tailed Student’s t test, n = 3. Data are representative of two independent experiments.