Table 2.
Results of Biochemical Testing Demonstrate Androgen-, Estrogen-, and Corticotrophin-Independent Cortisol Excess
| Laboratory Test | Before Surgery | 1 Mo After Surgery | Reference Range |
|---|---|---|---|
| 24-h Urine | |||
| Urine-free cortisol, μg/24 h | 68 | N/A | 3.5–45 |
| Serum | |||
| ACTH, pg/mL | <5 | N/A | 7.2–63 |
| 8 am Serum cortisol following 1 mg overnight dexamethasone suppression test, μg/dL |
13 | N/A | <1.8 |
| Aldosterone, ng/dL | 20 | N/A | ≤21 |
| Renin plasma activity, ng/mL/h | 2 | N/A | 0.6–3.0 |
| Androstenedione, ng/dL | 151 | N/A | 30–200 |
| DHEA sulfate, μg/dL | 403 | <15 | <15–157 |
| 17-Hydroxyprogesterone, ng/dL | 167 | <40 | <51 |
| 17-Hydroxypregnenolone, ng/dL | 888 | <16 | 31–455 |
| Total testosterone, ng/dL | 30 | <7 | 8–60 |
| Estradiol, pg/mL | 113 | <10 | <10 (Postmenopausal) |
Abbreviations: DHEA, dehydroepiandrosterone; N/A, not available.