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. Author manuscript; available in PMC: 2019 Apr 3.
Published in final edited form as: J Clin Psychopharmacol. 2017 Feb;37(1):89–93. doi: 10.1097/JCP.0000000000000626

Table 2.

Treatment dosage, adverse events, and symptom severity over time

Before treatment 3 months 6 months
Dosage
Prescribed, mean±SD, mg 38.33 ± 5.07 38.61 ± 4.87
Taken, mean±SD, mg 36.53 ± 6.64 37.78 ± 5.40
Adverse events, n, % 21 58.3% 6 16.7%
Change in appetite 2 5.6% 0 0%
Weight loss/gain 2 5.6% 1 2.7%
Abdominal pain 3 8.3% 2 5.6%
Diarrhea 4 11.1% 0 0%
Constipation 1 2.8% 0 0%
Dry mouth 2 5.6% 1 2.8%
Restlessness 0 0% 0 0%
Drowsiness 4 11.1% 1 2.8%
Insomnia 1 2.8% 0 0%
Headache 3 8.3% 0 0%
Vertigo 3 8.3% 0 0%
Sweating 2 5.6% 0 0%
Palpitations 1 2.8% 0 0%
Tremor 0 0% 0 0%
Sexual dysfunction 0 0% 0 0%
Other 15 42% 3 8.3%
CAPS total, mean±SD 71.80 ± 14.29 60.53 ± 24.60 60.08 ± 25.86
Intrusion 20.93 ± 4.41 17.06 ± 7.34 16.89 ± 7.79
Avoidance 28.16 ± 8.08 24.19 ± 11.96 23.36 ± 12.31
Hyperarousal 23.91 ± 3.84 19.28 ± 6.80 19.83 ± 6.91
BDI, mean±SD 25.71 ± 10.71 21.52 ± 11.84 21.86 ± 13.53