Table 1.
Detail of patients included in the study.
| Normoglycemic | T2D | |
|---|---|---|
| Number (n) | 30 | 65 |
| Age (years) | 71 ± 0.4 | 69 ± 0.9 |
| Gender (F%) | 13 (43) | 46 (35) |
| Fasting glucose (mg/dL) | 101.3 ± 1.2 | 171.7 ± 5.6* |
| Hb1Ac (%) | N/A | 7.37 ± 0.1 |
| BMI (kg/m2) | 26.3 ± 0.6 | 31.4 ± 0.8* |
| Waist Circumference | 91.3 ± 1.5 | 105.91 ± 1.74* |
| Total cholesterol (mg/dL) | 189.5 ± 4.8 | 187.27 ± 5.48 |
| HDL-C (mg/dL) | 59.7 ± 1.7 | 48.02 ± 1.85* |
| LDL-C (mg/dL, Friedewald) | 109.7 ± 4.3 | 109.61 ± 4.70 |
| Triglycerides (mg/dL) | 100.1 ± 5.3 | 148.26 ± 17.4* |
| C-Reactive Protein (mg/dL) | 0.12 ± 0.02 | 0.58 ± 0.2* |
| Alanine Aminotransfersae (ALT) (U/L) | 19.54 ± 0.96 | 31.89 ± 4.8* |
| Aspartate Aminotransferase (AST) (U/L) | 24.08 ± 0.61 | 26.71 ± 3.1* |
| Gamma Glutamyl Transpeptidase (GGT) (U/L) | 28.6 ± 3.15 | 35.16 ± 2.7* |
| Fatty Liver Index (%) | 37.1 ± 5.7 | 66.14 ± 3.31* |
| Creatinine (mg/dL) | 0.9 ± 0.04 | 1.8 ± 0.1* |
| GFR (mL/min) | 71.3 ± 2.34 | 29.7 ± 1.8* |
| Urinary albumin (mg/g urinary protein) | N/A | 202.0 ± 48.1 |
Number of patients per group, age, gender, fasting glucose, Hb1Ac, BMI, waist circumference serum, cholesterol, HDL, LDL-C, triglyceride, C-reactive protein (CRP), ALT, AST, GGT, FLI, creatinine, GFR, and urinary albumin. Experimental groups: Normoglycemic (n = 30) and patients with type-2 diabetes T2D, (n = 65). Data analyzed by unpaired Student's t-test (normally distributed data) or Mann Whitney U-test (data that are not normally distributed) and expressed as mean ± SEM.
*
p < 0.05; NA, data not available.