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Ingestion of water and salt in depleted rats activates hypothalamic Ox neurons and the VTA. The percentage of Ox neurons that expressed FLI was greater in rats that were depleted and allowed to drink water and sodium across each Ox cluster (*=p<.05). The VTA also exhibited a greater amount of FLI expression in this condition. FLI, Fos-like immunoreactivity; Ox, orexin; VTA, ventral tegmental area.
