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Antagonism of Ox type 1 receptors within the VTA attenuates fluid intake in depleted rats. Compared to vehicle (n=6) pretreated rats, rats pretreated with SB-408124 (n=5) exhibited reduced total fluid intake (A; *=p<.05). Scatterplots display variability in water (B) and sodium (C) intake across treatment conditions. OX, orexin; VTA, ventral tegmental area.
