Table 1.

Advantages and disadvantages of viral vectored vaccines, DNA vaccines and RNA vaccines.

Vaccines	Advantages	Disadvantages
Viral vectored vaccines	Stimulation of innate immune response; induction of T and B cell immune response.	induction of anti-vector immunity: cell based manufacturing
DNA vaccines	Non-infectious; stimulation of innate immune response; egg and cell free; stable, rapid and scalable production; induction of T and B cell immune response.	Potential integration into human genome; poor immunogenicity in humans.
RNA vaccines	Non-infectious, non-integrating, natural degradation, egg and cell free, rapid and scalable production; stimulation of innate immune response; induction of T and B cell immune response.	Concerns with instability and low immunogenicity.