. 2019 Jan 15;4(1):e00329-18. doi: 10.1128/mSystems.00329-18

TABLE 1.

Summary of the gene-based comparisons of the CFA/I and CS6 genomes

Group 1^a	Group 2	No. of genomes in group 1	No. of genomes in group 2	No. of gene clusters^b
Group 1^a	Group 2	No. of genomes in group 1	No. of genomes in group 2	All genomes	≥50% genomes	≥1 genome
CFA/I	CS6	142	87	2	193	1,771
CS6	CFA/I	87	142	4	107	2,327
CFA/I	CS6⁺ reference ETEC	142	124	2	123	1,379
CS6	CFA/I⁺ reference ETEC	87	179	4	42	1,227
Phylogroup A CFA/I	Phylogroup B1 CFA/I	119	22	100	422	2,091
Phylogroup B1 CFA/I	Phylogroup A CFA/I	22	119	137	478	1,142
CFA/I ETEC lineage L3	Other CFA/I	21	121	119	243	665
CFA/I ETEC lineage L6	Other CFA/I	105	37	146	260	1,201
CFA/I ETEC lineage L15	Other CFA/I	14	128	157	270	420
Phylogroup A CS6	Phylogroup B1 CS6	16	71	22	361	1,407
Phylogroup B1 CS6	Phylogroup A CS6	71	16	58	307	2,246
CS6 ETEC lineage L4	Other CS6	9	78	136	166	380
CS6 ETEC lineage L5	Other CS6	53	34	50	139	982
CS6 ETEC lineage L8	Other CS6	16	71	104	267	459

The de novo LS-BSR analysis included 142 CFA/I genomes (ST⁺, LT⁻, and CFA/I⁺), 87 CS6 genomes (ST⁺, LT⁻, and CS6⁺), and 37 reference ETEC genomes (LT⁺ and/or ST⁺ but not containing CFA/I or CS6). There were 3,567 gene clusters identified with significant similarity (BSR of ≥0.9) in all 266 ETEC genomes analyzed (CS6, CFA/I, and reference ETEC).

Data represent numbers of gene clusters that were present in all genomes, ≥50% of the genomes, or ≥1 of the genomes of group 1 (BSR of ≥0.9) and absent from all of the genomes of group 2 (BSR of <0.4).