Table 2: Breast and Ovarian Surveillance Service (BOSS) ER S118P carrier characteristics.
S118P carrier characteristics within a cohort of individuals with a family history of breast cancer.
| Variable | ER S118 WT (N=532) | ER S118P (N=4) |
|---|---|---|
| Breast cancer survivor, % | 50.0 | 50.0 |
| Age at baseline, years, mean (SD) | 50.3 (11.2) | 52.2 (13.0) |
| Postmenopausal, % | 52.3 | 75.0 |
| Age at menopause, years, mean (SD) | 49.2 (5.8) | 52.3 (9.1) |
| BMI, kg/m2, mean(SD) | 26.6 (6.1) | 26.0 (4.9) |
| Physical activity, MET-h/week mean (SD)a | 27.1 (31.1) | 19.3 (22.8) |
| Alcohol intake, mean (SD) | 6.3 (10.1) | 4.1 (3.9) |
| Smoking, % | ||
| Never | 57.1 | 0 |
| Former | 37.8 | 100.0 |
| Current | 4.5 | 0 |
| Missing | <1 | 0 |
a
metabolic equivalents from recreational and occupational activity