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. Author manuscript; available in PMC: 2019 Apr 3.
Published in final edited form as: J Allergy Clin Immunol. 2015 Oct 29;137(3):789–96.e7. doi: 10.1016/j.jaci.2015.08.045

Table I.

Features of the Study Sample Stratified by the Ventilation Defect /Total Lung Volume Tercile Distribution

Variable Sample Lower Tercile (0.13 – 0.81%) Middle Tercile (1.0–2.1%) Upper Tercile (2.5–11.6%) p
n 31 10 11 10
Enrollment Age (yr) 10 (3–17) 9 (4–16) 11 (3–17) 9 (3–17) 0.97**
Male sex n (%) 21 (68%) 7 (70%) 7 (64%) 7 (70%) 0.94
African American n (%) 10 (32%) 2 (20%) 4 (36%) 4 (40%) 0.48
Body Mass Index (kg/m2) 18.3 (14.7–33.6) 18.5 (17.1–29.0) 17.5 (14.7–33.6) 19.6 (14.7–31.5) 0.77
Birth Gestational Age (mo) 39 (24–39) 38 (28–39) 38 (27–39) 39 (24–39) 0.66
Age at First Wheeze (mo) 12 (2–108) 12 (2–60) 12 (2–24) 8 (2–108) 0.89
Hospital Admissions for Asthma (n) 1 (0–10) 1 (0–6) 1 (0–10) 6 (1–6) 0.16
Any ICU Admission for Asthma n (%) 8 (26%) 2 (20%) 2 (18%) 4 (40%) 0.46
Any Past Pneumonia n (%) 26 (84%) 8 (80%) 10 (91%) 8 (80%) 0.73
Family History Asthma n (%) 24 (77%) 9 (90%) 8 (73%) 7 (70%) 0.51
Daily ICS Dose (mcg fluticasone equiv.) 800 (0–2000) 445 (0–920) 460 (320 −2000) 860 (80–1600) 0.08
High Dose ICS n (%) 25 (81%) 6 (60%) 10 (91%) 9 (90%) 0.13
Daily Prednisone n (%) 7 (23%) 0 (0%) 2 (18%) 5 (50%) 0.03
Daily LABA n (%) 22 (71%) 5 (50%) 8 (73%) 9 (90%) 0.14
Montelukast n (%) 20 (64%) 5 (50%) 8 (73%) 7 (70%) 0.50
# Daily Controllers 3 (1–4) 2 (1–4) 3 (1–4) 4 (1–4) 0.05
cACT/ACT score 12 (8–25) 14 (11–25) 11 (8–23) 12 (9–14) 0.21
Asthma Event Score 0.83 (0.0–3.0) 0.83 (0.25–1.5) 0.66 (0.0–2.8) 0.87 (0.0–3.0) 0.84
Severe Asthma n (%) 20 (64%) 3 (30%) 7 (64%) 10 (100%) 0.005
*

Scaled variables shown as the median (min-max values);

**

Kruskal Wallis test corrected for multiple group comparisons.