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. Author manuscript; available in PMC: 2019 Apr 3.
Published in final edited form as: Cell Rep. 2019 Feb 26;26(9):2394–2406.e5. doi: 10.1016/j.celrep.2019.02.017

Figure 5. MCMV Infection Promotes EMH in the Absence of IFNAR1 or IFNGR2 in Myeloid Cells and in the Complete Absence of IL-27Rα.

Figure 5.

(A–C, F–H, and K–M) Spleen weight (A, F, and K), (B, G, and L) cellularity, and (C, H, and M) total number of erythroblasts per spleen of Ifngr2ΔM/PMN, Ifnra1ΔM/PMN, and Il27ra−/− mice 5 days after MCMV infection.

(D, I, and N) Erythrocyte precursor composition among erythroblasts in spleens according to size and CD44 expression (day 5 p.i.).

(E, J, and O) Blood platelet counts determined with a Vet ABC analyzer (day 5 p.i.).

In (A)–(E) and (K)–(O), n = 8–14, N = 2; and in (F)–(J), n = 17–19, N = 3. Mean values ± SEM are given. *p ≤ 0.05, **p ≤ 0.01, and ***p ≤ 0.001 (statistical significance between the genotypes); #p ≤ 0.05, ##p ≤ 0.01, ###p ≤ 0.001, and ####p ≤ 0.0001 (statistical significance relative to the PBS control). n, biological replicates; N, experimental repetitions.