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. 2019 Feb 11;100(4):921–931. doi: 10.4269/ajtmh.17-0945

Table 1.

Summary of the salient clinical, histopathological, and imaging characteristics of the eight patients

Case Affected limb Skin lesions Cranial nerve involvement Site of biopsy; nerve /skin lesion Duration of illness Histological diagnosis Acid-fast bacilli in nerve tissue/skin PCR for lepra DNA (nerve) PCR for 16S rRNA gene (cerebrospinal fluid) Magnetic resonance imaging lesion (s) On multidrug therapy before biopsy (duration) Follow-up
1 All four limbs Yes VII Left SRN; skin from leg 8 years BT No Positive Negative Facial nuclei and nerve; bilateral BP (Figure 2) Yes 16 months
2 Left hand; skin Yes No Left SRN 6 months BT No Positive Negative C6–C7; left BP (Figure 4) No 8 months
3 Upper limbs Yes No Left DCUN 3 years BL Yes Positive Not done C3; bilateral BP No 2 months
4 Right upper limb Yes No Left SRN 3 years BT No Positive Positive C4–C5 hemicord lesion; bilateral BP Yes 4 months
5 Right upper limb No No Left sural nerve 1 year BL Yes Positive Not done C4–D2; bilateral BP (Figure 7) No No
6 Left lower limb Yes No Left sural; skin from leg 2 months BT Yes Positive Not done Left conus, lumbar plexus (Figure 7) No No
7 Left upper limb Yes No Left SRN 9 months BT No Positive Not done Left C5–C6 (Figure 7) No No
8 All four limbs Yes V, VII, IX, and X Left SRN 8 months BT No Positive Negative Facial nuclei and nerves, cord C2–C3, D4–D5, D7–D8, D11–D12; bilateral brachial plexus and lumbar plexus (Figure 8) No No

BL = bilateral; BT = borderline tuberculoid; DCUN = dorsal cutaneous ulnar nerve; PCR = polymerase chain reaction; SRN = superficial radial nerve.