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Fold changes (FC) in expression of fibroblast growth factor 7 (FGF-7), myelin basic protein (MBP), and peripheral myelin protein 22 (PMP-22) relative to untreated controls (Con). Schwann cells were stimulated with transforming growth factor beta 1 (TGF-β1) + forskolin (T/F) alone or with T/F and LY2109761 (T/F+I), a TGF-β receptor type I/II (TβR1/II) inhibitor, for 6 hours (n=3). Blocking of TβR1/II decreased the effect of T/F treatment on FGF-7 expression (P<0.05).
