Table 3. Clinicopathological parameters.
| WEEK 1 | WEEK 2 | WEEK 3 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| PARAMETER | Cy n = 58 |
Dim n = 51 | Iso n = 53 | Cy n = 54 |
Dim n = 48 | Iso n = 49 | Cy n = 50 |
Dim n = 44 | Iso n = 45 | |
| HAEMATOCRIT (%) | Horse | 20 (19–24) |
20 (13–24) |
20 (15–23) |
22 (20–23) |
24 (19–27) |
24 (21–27) |
22 (18–23) |
22 (20–28) |
28 (24–28) |
| ≤30% | 20/21 (95%) | 16/16 (100%) | 18/18 (100%) | 21/21 (100%) | 14/15 (93%) | 16/17 (94%) | 18/18 (100%) | 10/11 (91%) | 13/15 (87%) | |
| Donkey | 20 (16–24) |
20 (16–23) |
20 (16–23) |
22 (20–26) |
23 (21–27) |
23 (21–26) |
23 (21–25) |
26 (23–28) |
26 (22–28) |
|
| ≤26% | 37/37 (100%) | 32/35 (91%) | 34/35 (97%) | 25/33 (76%) | 24/33 (73%) | 25/32 (78%) | 27/ 32 (84%) | 19/33 (58%) | 18/30 (60%) | |
|
TOTAL PROTEIN (G/L) |
Horse | 80 (70–90) |
77 (70–87) |
88 (76–92) |
90 (82–100) |
84 (80–93) |
96 (88–105) |
96 (81–103) |
81 (78–93) |
100 (93–104) |
| Donkey | 82 (75–90) |
82 (75–90) |
80 (75–87) |
98 (86–105) |
96 (90–105) |
98 (90–105) |
100 (92–106) | 96 (87–106) |
95 (90–106) |
Haematocrit (%) and total plasma protein (g/l) for the whole treatment population (n = 162) subdivided by trypanocidal drug group (melarsomine dihydrochloride (Cy), diminazene (Dim), isometamidium (Iso) are presented by species (horse and donkey) and time point (week 1, 2 and 3). Parameters are presented as median and IQR and categorised as within or outside the reference range (proportion and percentage).