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. 2019 Apr 2;39(8):e00432-18. doi: 10.1128/MCB.00432-18

TABLE 1.

Genes whose mRNA levels changed in the tDNA delete strain compared to the wild type and statistical analysis of the differences in expression levels

Gene Q value
Beta statistic Gene product function
Likelihood ratio test Wald test
Upregulated
    YCR061w 0.042003857 3.22E−11 0.6580998 Protein of unknown function
    YDL124w 0.042003857 6.31E−14 0.4395261 NADPH-dependent alpha-keto amide reductase
    YHR214c-B 0.005672182 2.35E−210 2.5870238 Retrotransposon TYA Gag and TYB Pol genes
    YNL160w 0.040272092 2.69E−20 0.5348964 YGP1 Cell wall-related secretory glycoprotein
    YOR201c 0.020396347 9.18E−27 0.7685378 MRM1 Ribose methyltransferase
    YOR202w 0.009117145 1.20E−76 3.7326308 HIS3 Imidazoleglycerol-phosphate dehydratase
    YPL240c 0.042003857 1.20E−15 0.5188043 HSP82 Hsp90 chaperone
Downregulated
    YBR068c 0.030966243 1.53E−20 −0.5156825 BAP2 High-affinity leucine permease
    YBR296c 0.039894621 1.87E−19 −0.5692597 PHO89 Plasma membrane Na+/Pi cotransporter
    YCR008w 0.015662463 6.48E−43 −1.1217 SAT4 Ser/Thr protein kinase involved in salt tolerance
    YER073w 0.045197971 8.81E−16 −0.5691673 ALD5 Mitochondrial aldehyde dehydrogenase
    YER091c 0.042003857 1.79E−20 −0.5345605 MET6 Cobalamin-independent methionine synthase
    YGL009c 0.009117145 1.47E−82 −2.0202761 LEU1 Isopropylmalate isomerase
    YHR208w 0.007776891 7.72E−106 −1.3235331 BAT1 Mitochondrial branched-chain amino acid aminotransferase
    YJR010w 0.042003857 3.34E−13 −0.8073784 MET3 ATP sulfurylase involved in methionine metabolism
    YJR016c 0.017736878 3.09E−29 −0.5823368 ILV3 Dihydroxy acid dehydratase involved in biosynthesis of branched-chain amino acids
    YKL030w 0.042003857 3.46E−11 −0.6718075 Dubious open reading frame
    YKL120w 0.007776891 1.47E−94 −1.4546702 OAC1 Mitochondrial inner membrane transporter
    YLR355c 0.042003857 2.35E−12 −0.387429 ILV5 Acetohydroxy acid reductoisomerase involved in biosynthesis of branched-chain amino acids
    YMR108w 0.042003857 3.72E−15 −0.4213145 ILV2 Acetolactate synthase involved in isoleucine and valine biosynthesis
    YOR271c 0.027535084 4.63E−26 −0.5903308 FSF1 Putative protein of the sideroblastic-associated protein family