Figure 4. Best structures of CS-Rosetta for each segment.
(A) SET and segment I. One predicted structure is shown in ribbon diagram. SET is in black, and segment I in red. (B) Segment III shows collapsed coils. The ITIMs in one representative structure are shown. (C) Segment II (352-MDQEPAGNRTANSEDSDEQD-371). C1: six structures show a matched loop; C2: two structures with alternative loop conformations; C3: two structures with extended β-strand. Common orientations of end residues M352 and D371 in the majority of structures are marked. T361 is also marked.