Table 3:
Liver histopathology scoring from the intraperitoneal 60 μg/kg MCLR toxicity experiment in control, MCD, and HFHC rats.
| Control | MCD | HFHC | p-value | |
|---|---|---|---|---|
| Steatosis | 0.0 (0.0) | 4.0 (0.8)* | 3.0 (0.0)* | <0.0001 |
| Inflammation | 2.3 (0.3) | 1.5 (0.5) | 3.0 (0.0) | 0.0107 |
| Necrosis | 2.7 (0.3) | 1.0 (1.0)* | 3.3 (0.3) | 0.0045 |
| Apoptosis | 2.3 (0.3) | 1.3 (0.3)* | 2.0 (0.0) | 0.0355 |
Data represent mean ± SD. Control and HFHC, n=3 per group; MCD, n=4. One-way ANOVA p-values are shown below each pathology score graph.
p-value <0.05 versus control and according to Tukey’s multiple comparison post-test.