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. Author manuscript; available in PMC: 2020 Apr 15.
Published in final edited form as: Toxicon. 2019 Mar 5;162:1–8. doi: 10.1016/j.toxicon.2019.03.002

Table 4:

Kidney histopathology scoring from the intraperitoneal 60 μg/kg MCLR toxicity experiment in control, MCD, and HFHC rats.

Control MCD HFHC p-value
Overall score 1.3 (0.9) 0.5 (0.6) 1.7 (0.3) 0.2491
Necrosis 0.7 (0.3) 0.0 (0.0) 0.3 (0.3) 0.2039
Degeneration 0.7 (0.3) 0.0 (0.0) 0.7 (0.3) 0.1278
Regeneration 0.3 (0.3) 0.0 (0.0) 0.7 (0.3) 0.2039
Tubule dilation 1.0 (0.6) 0.0 (0.0) 1.3 (0.3) 0.0299
Casts 1.3 (0.9) 0.0 (0.0) 1.7 (0.3) 0.0338
Glomerular change 1.0 (1.0) 0.8 (0.9) 1.7 (0.3) 0.5388

Data represent mean ± SD. Control and HFHC, n=3 per group; MCD, n=4. One-way ANOVA p-values are shown below each pathology score graph.