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. Author manuscript; available in PMC: 2020 Apr 2.
Published in final edited form as: Structure. 2019 Feb 14;27(4):606–617.e5. doi: 10.1016/j.str.2019.01.008

Figure 1. Prediction robustness to small differences in input structures.

Figure 1.

Distribution of Pearson correlation coefficients (R) that reflect the similarity of scores generated from structurally similar templates (binding mode RMSD < 1 Å; see Table S3). 294 pairs of structures and 6155 unique sequences were used to generate the data. The median R value is indicated with a line, data between the first and third quartiles (Q1-Q3) are within the box, the whiskers represent extensions of Q1 and Q3 by 1.5 times the interquartile distance (Q1-Q3), and outliers show points outside the whiskers. The larger correlation coefficients obtained when using dTERMen, compared to other methods, indicate lower sensitivity to small structural differences in templates.