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. Author manuscript; available in PMC: 2020 Apr 2.
Published in final edited form as: Structure. 2019 Feb 14;27(4):606–617.e5. doi: 10.1016/j.str.2019.01.008

Figure 4. Comparison of the structures of designed complexes and their templates.

Figure 4.

X-ray crystal structures of (A) dF1 bound to Bfl-1, (B) dF4 bound to Bfl-1, (C) dM1 bound to Mcl-1, and (D) dM7 bound to Mcl-1 (all with the peptide in purple) are compared to the template structures on which they were designed (green ribbon and gray surface). The N-terminal end of each peptides lies to the left in the figure. For further structural analysis, see Fig. S6.