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. Author manuscript; available in PMC: 2020 May 15.
Published in final edited form as: Int J Biol Macromol. 2019 Feb 13;129:653–658. doi: 10.1016/j.ijbiomac.2019.02.070

Figure 1. Structure of molecules identified as TrEH inhibitors.

Figure 1.

Molecules 2-5 were identified and the IC50 was determined by De Oliveira et al [17]. All inhibitors have an urea or amide group that might mimic an epoxide group in the active site of the enzyme.