Table 1.
Descriptive characteristics of the 5 randomized, controlled trials included in the pilot study.
| INFINITE (N=180) | I’M FIT (N=126) | SECRET (N=51) | IDEA (N=302) | CLIP (N=195) | |
|---|---|---|---|---|---|
| Enrollment period | 10/2009 – 8/2014 | 5/2010 – 12/2013 | 1/2009 – 9/2012 | 10/2006 – 6/2011 | 1/2005 – 4/2010 |
| Sample size | |||||
| EX only, N | 61 | 63 | 26 | 150 | 97 |
| CR+EX, N | 119 | 63 | 25 | 152 | 98 |
| Age, mean (SD), years | 69.1 (3.5) | 69.9 (3.7) | 67.4 (5.5) | 65.5 (6.2) | 67.0 (4.8) |
| Age range, years | 65-79 | 65-79 | 60-82 | 55-85 | 60-79 |
| Female gender, % | 76.3% | 55.0% | 80.6% | 66.2% | 72.0% |
| White race, % | 75.6% | 89.2% | 56.6% | 82.7% | 80.2% |
| BMI, mean (SD), kg/m2 | 34.4 (3.4) | 31.0 (2.4) | 40.4 (7.0) | 33.6 (3.7) | 33.7 (4.4) |
| BMI range, kg/m2 | 30-45 | 27-35 | ≥30 | ≥27 | ≥30 |
| Intervention | AT vs CR+AT | RT vs CR+RT | AT vs CR+AT | AT/RT vs CR+AT/RT | AT vs CR+AT |
| Weight loss goal | 5-11% | 8-10% | 10-15% | 10-15% | 7-10% |
| Achieved weight loss | |||||
| EX only, % | −1.5% | −0.2% | −3.1% | −2.0% | −1.0% |
| CR+EX, % | −9.0% | −5.7% | −9.7% | −11.4% | −7.7% |
| Intervention duration | 5 months | 5 months | 5 months | 18 months* | 18 months* |
| Number recalled (EX only / CR+EX) | 13 (7 / 6) | 8 (4 / 4) | 5 (3 / 2) | 20 (11 / 9) | 14 (8 / 6) |
| Age, mean (SD), years | 68.1 (2.3) | 69.1 (2.8) | 68.2 (5.3) | 65.3 (4.7) | 66.6 (4.8) |
| Female gender, % | 61.5% | 87.5% | 80.0% | 70.0% | 50.0% |
| White race, % | 84.6% | 100% | 60.0% | 95.0% | 71.4% |
*
Intensive weight loss phase during the first 6 months; continued weight loss, if safe (<20% between 6 and 12 months and <30% after 12 months in IDEA; BMI >20 kg/m2 in CLIP), and/or weight maintenance during the second 12 months.
Abbreviations: EX, exercise; CR, caloric restriction; AT, aerobic training; RT, resistance training; SD, standard deviation.