Table 3.

Listing of statistically significant pairwise comparisons of each ketamine group to midazolam

Measure	Day	Dose group	b	95% CI	Raw p	Adj. p	Cohen’s d
MADRS
	Day 3	0.5 mg/kg	−9.85	(−16.56, −3.15)	0.00	0.02*	−1.03
CGI-S
	Day 1	0.5 mg/kg	−1.28	(−2.02, −0.54)	0.00	0.01*	−1.21
	Day 1	1.0 mg/kg	−1.05	(−1.81, −0.29)	0.01	0.05*	−1.11
CGI-I
	Day 1	0.5 mg/kg	−0.98	(−1.64, −0.31)	0.00	0.03*	−1.27
SDQ
	Day 1	0.5 mg/kg	−0.61	(−1.01, −0.21)	0.003	0.0243*	−0.95
PAS
	Day 1	0.5 mg/kg	16.54	(5.31, 27.77)	0.0043	0.0347*	0.94

MADRS Montgomery–Asberg Depression Rating Scale, CGI-S and CGI-I Clinical Global Impression of Severity and Improvement scales, SDQ Symptoms of Depression Questionnaire, PAS Positive Affect Scale

^*Adj. p < 0.05