Table 1.
Univariate and multivariate Cox regression analyses of the serum core-fucosylated QSOX1 for time to recurrence (TTR) of patients in the set C (N = 60) of cohort A
| Variables in the equation | Stratification standard | TTR | |||
|---|---|---|---|---|---|
| p-Value | Hazard ratio | 95% CI | |||
| Lower | Upper | ||||
| Univariate analysis | |||||
| Sex | Male vs. female | 0.591 | 1.5 | 0.4 | 6.3 |
| Age | 50 vs. ≤50 | 0.317 | 0.7 | 0.3 | 1.4 |
| AFP | 20 vs. ≤20 ng/ml | 0.896 | 1.1 | 0.5 | 2.2 |
| Liver cirrhosis | Microndular vs. macrondular | 0.042 | 2.3 | 1.0 | 4.9 |
| Tumor size | <2 vs. ≥2 cm | 0.902 | 1.1 | 0.5 | 2.4 |
| Microvascular invasion | Yes vs. no | 0.536 | 1.5 | 0.4 | 5.1 |
| Tumor encapsulation | Yes vs. no | 0.524 | 1.3 | 0.6 | 2.6 |
| Tumor differentiation | I–II vs. III–IV | 0.761 | 1.1 | 0.5 | 2.4 |
| BCLC stage | 0 vs. A | 0.902 | 1.1 | 0.5 | 2.4 |
| Okuda stage | I vs. II | 0.179 | 4.0 | 0.5 | 30.8 |
| CLIP score | 0 + 1 vs. 2 + 3 | 0.233 | 3.4 | 0.5 | 25.9 |
| cf-QSOX1 | High vs. Low | 0.042 | 0.5 | 0.2 | 1.0 |
| Multivariate analysis | |||||
| cf-QSOX1 | High vs. low | 0.047 | 0.5 | 0.2 | 1.0 |
| Liver cirrhosis | Microndular vs. macrondular | 0.047 | 2.2 | 1.0 | 4.8 |
95% CI 95% confidence interval, AFP α-fetoprotein, cf-QSOX1 core-fucosylated QSOX1.
The meaning of the bold P values is that they are under 0.05 and statistically significant