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. 2019 Apr 3;10:1522. doi: 10.1038/s41467-019-09320-9

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — A distribution of ERα and CTCF peaks in E2-induced TDRCs and TRACs. a The number of ERα peaks. b Heatmap showing the percentage of altered TamR compartments A (Left) and B (Right) with ERα peaks. c The number of CTCF peaks. The legend is the same as (a). d The average of CTCF peaks on altered TamR compartment boundary in E2-induced five time points and TamR MCF cell lines. e The distribution of each of 24 patterns (circled) of ERα peaks within compartments and CTCF peaks on compartment boundary in E2-induced MCF7 cells (left) and in TamR cells (right). CTCF CCCTC-binding factor, TDRC temporally dynamic re-compartmentalization, TRAC tamoxifen-resistant altered compartment