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. 2019 Apr 3;10:1517. doi: 10.1038/s41467-019-09252-4

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Separation of samples using beta diversity data based on age and gestational age at birth. a Principal coordinate analysis (PCoA) based on Bray–Curtis operational taxonomic unit (OTU) data on independent samples at years one, two and four (individuals sampled at one time point). b PCoA based on Bray–Curtis OTU data on independent samples based on gestational age at birth. c Adonis variance analysis based on Bray–Curtis distance matrices at OTU level. Source data are provided as a Source Data file. (*p < 0.05, **p < 0.01, ***p < 0.001)